First natural urease inhibitor from Euphorbia decipiens.
نویسندگان
چکیده
Three new diterpene esters with a myrsinol-type skeleton have been isolated from Euphorbia decipiens BOISS. & BUHSE. The structure elucidation of the isolated compounds was based primarily on two-dimensional (2D)-NMR techniques including correlation spectroscopy (COSY), heteronuclear multiple quantum coherence (HMQC), heteronuclear multiple bond correlation (HMBC) and nuclear Overhauser effect spectroscopy (NOESY) experiments. Compounds 1 and 3 are active against prolyl endopeptidase and compound 2 showed inhibitory activity against urease enzyme.
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ورودعنوان ژورنال:
- Chemical & pharmaceutical bulletin
دوره 51 6 شماره
صفحات -
تاریخ انتشار 2003